Feng‐Zhi Suo

Development of the triazole-fused pyrimidine derivatives as highly potent and reversible inhibitors of histone lysine specific demethylase 1 (LSD1/KDM1A)

Zhonghua Li, Lina Ding, Zhongrui Li et al. · Acta Pharmaceutica Sinica B · 2019 · 78 citations · Full text

Discovery of [1,2,3]Triazolo[4,5-<i>d</i>]pyrimidine Derivatives as Novel LSD1 Inhibitors

Zhonghua Li, Xue‐qi Liu, Peng Geng et al. · ACS Medicinal Chemistry Letters · 2017 · 73 citations · Full text

Synthesis, structure-activity relationship studies and biological characterization of new [1,2,4]triazolo[1,5-a]pyrimidine-based LSD1/KDM1A inhibitors

Shuai Wang, Zhong‐Rui Li, Feng‐Zhi Suo et al. · European Journal of Medicinal Chemistry · 2019 · 57 citations · Full text

Biochemistry, Medicine, Rational Drug Design +7

Natural protoberberine alkaloids, identified as potent selective LSD1 inhibitors, induce AML cell differentiation

Zhongrui Li, Feng‐Zhi Suo, Yan-Jia Guo et al. · Bioorganic Chemistry · 2020 · 48 citations

Natural Protoberberine Alkaloids, Medicine, Mechanism Of Action +6

Identification of osimertinib (AZD9291) as a lysine specific demethylase 1 inhibitor

Zhongrui Li, Feng‐Zhi Suo, Bo Hu et al. · Bioorganic Chemistry · 2018 · 42 citations

Medicinal Chemistry, Drug Target, Biochemistry +10