Janis E. Shackelford

Mevalonate kinase is predominantly localized in peroxisomes and is defective in patients with peroxisome deficiency disorders.

Lenka Biardi, Amere Subbarao Sreedhar, A. Zokaei et al. · Journal of Biological Chemistry · 1994 · 88 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Localization of the pre-squalene segment of the isoprenoid biosynthetic pathway in mammalian peroxisomes

Werner J. Kovacs, Khanichi N. Tape, Janis E. Shackelford et al. · Histochemistry and Cell Biology · 2006 · 85 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Peroxisome Deficiency Causes a Complex Phenotype because of Hepatic SREBP/Insig Dysregulation Associated with Endoplasmic Reticulum Stress

Werner J. Kovacs, Khanichi N. Tape, Janis E. Shackelford et al. · Journal of Biological Chemistry · 2008 · 66 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Subcellular localization of squalene synthase in rat hepatic cells. Biochemical and immunochemical evidence

K.D. Stamellos, Janis E. Shackelford, Ishaiahu Shechter et al. · Journal of Biological Chemistry · 1993 · 64 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Disturbed Cholesterol Homeostasis in a Peroxisome-Deficient <i>PEX2</i> Knockout Mouse Model

Werner J. Kovacs, Janis E. Shackelford, Khanichi N. Tape et al. · Molecular and Cellular Biology · 2003 · 62 citations · Full text

Life Sciences, Biochemistry, Genetics +17