Raoul Tibes

Inhibition of the Hedgehog Pathway in Advanced Basal-Cell Carcinoma

Daniel D. Von Hoff, Patricia LoRusso, Charles M. Rudin et al. · New England Journal of Medicine · 2009 · 1.1K citations · Full text

Medicine, Oncology, Pharmacology +17

Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells

Raoul Tibes, Yihua Qiu, Yiling Lu et al. · Molecular Cancer Therapeutics · 2006 · 758 citations

Life Sciences, Cell Biology, Molecular Biology +17

Phase I Trial of Hedgehog Pathway Inhibitor Vismodegib (GDC-0449) in Patients with Refractory, Locally Advanced or Metastatic Solid Tumors

Patricia LoRusso, Charles M. Rudin, Josina C. Reddy et al. · Clinical Cancer Research · 2011 · 547 citations · Full text

Medicine, Oncology, Pharmacology +17

Selective inhibition of FLT3 by gilteritinib in relapsed or refractory acute myeloid leukaemia: a multicentre, first-in-human, open-label, phase 1–2 study

Alexander E. Perl, Jessica K. Altman, Jörge E. Cortes et al. · The Lancet Oncology · 2017 · 488 citations · Full text

Medicine, Oncology, Pharmacology +10

The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia

Eytan M. Stein, Guillermo Garcia‐Manero, David A. Rizzieri et al. · Blood · 2018 · 457 citations · Full text

Life Sciences, Molecular Biology, Oncology +10