Jacob Thomas

Dysregulated expression of monoacylglycerol lipase is a marker for anti-diabetic drug metformin-targeted therapy to correct impaired neurogenesis and spatial memory in Alzheimer's disease

Charvi Syal, Jayasankar Kosaraju, Laura K. Hamilton et al. · Theranostics · 2020 · 40 citations · Full text

A phase I study to evaluate the safety, pharmacokinetics, and pharmacodynamics of PF-06939999 (PRMT5 inhibitor) in patients with selected advanced or metastatic tumors with high incidence of splicing factor gene mutations

Jordi Rodón, Estelamari Rodríguez, Michael L. Maitland et al. · ESMO Open · 2024 · 37 citations · Full text

Molecular profiling of melanoma brain metastases compared to primary cutaneous melanoma and to extracranial metastases

Gino K. In, Kelsey Poorman, Michelle Saul et al. · Oncotarget · 2020 · 33 citations · Full text

A first-in-human study of AO-176, a highly differentiated anti-CD47 antibody, in patients with advanced solid tumors.

Howard A. Burris, Alexander I. Spira, Matthew H. Taylor et al. · Journal of Clinical Oncology · 2021 · 27 citations

Anti-cd47 Antibody, Immunology, Immune Regulation +23

A phase I study of intravenous fenretinide (4-HPR) for patients with malignant solid tumors

Jacob Thomas, Anthony B. El-Khoueiry, Barry J. Maurer et al. · Cancer Chemotherapy and Pharmacology · 2021 · 20 citations · Full text

Surgical Oncology, Oncology, Medicine +9