Philip Lecane

Role of glutathione depletion and reactive oxygen species generation in apoptotic signaling in a human B lymphoma cell line

Jeffrey S. Armstrong, Kirsten K Steinauer, Brita Hornung et al. · Cell Death and Differentiation · 2002 · 496 citations · Full text

Reductive Stress, Glutathione Depletion, Apoptosis +12

ATM Activation and Signaling under Hypoxic Conditions

Zuzana Bencokova, Muriel Kaufmann, Isabel M. Pires et al. · Molecular and Cellular Biology · 2008 · 201 citations · Full text

Atm Activation, Molecular Biology, Cell Cycle +18

Antiproliferative and proapoptotic activities of triptolide (PG490), a natural product entering clinical trials, on primary cultures of human prostatic epithelial cells.

Taija M. Kiviharju, Philip Lecane, Robert G. Sellers et al. · PubMed · 2002 · 181 citations

Urology, P53 Target Genes, Chemoprevention Strategy +15

Synthesis and Anticancer Properties of Water-Soluble Zinc Ionophores

Darren Magda, Philip Lecane, Zhong Wang et al. · Cancer Research · 2008 · 96 citations · Full text

Motexafin gadolinium generates reactive oxygen species and induces apoptosis in sensitive and highly resistant multiple myeloma cells

Andrew M. Evens, Philip Lecane, Darren Magda et al. · Blood · 2004 · 85 citations · Full text