Jane E. Willoughby

Conformation of the Human Immunoglobulin G2 Hinge Imparts Superagonistic Properties to Immunostimulatory Anticancer Antibodies

Ann L. White, H.T. Claude Chan, Ruth R. French et al. · Cancer Cell · 2014 · 171 citations · Full text

Pharmacy, Immunology, Oncology +14

Antibodies to Costimulatory Receptor 4-1BB Enhance Anti-tumor Immunity via T Regulatory Cell Depletion and Promotion of CD8 T Cell Effector Function

Sarah L. Buchan, Lang Dou, Marcus Remer et al. · Immunity · 2018 · 153 citations · Full text

Life Sciences, Immunology, Oncology +14

Sustained TL1A expression modulates effector and regulatory T-cell responses and drives intestinal goblet cell hyperplasia

Vadim Y. Taraban, Tomasz Ślebioda, Jane E. Willoughby et al. · Mucosal Immunology · 2010 · 95 citations · Full text

Life Sciences, Cell Biology, Immunology +16

Akt signaling is critical for memory CD8 ⁺ T-cell development and tumor immune surveillance

Anne Rogel, Jane E. Willoughby, Sarah L. Buchan et al. · Proceedings of the National Academy of Sciences · 2017 · 61 citations · Full text

Life Sciences, Immunology, Oncology +12

Triggering of TNFRSF25 promotes CD8⁺ T‐cell responses and anti‐tumor immunity

Tomasz Ślebioda, Tania F. Rowley, John R. Ferdinand et al. · European Journal of Immunology · 2011 · 60 citations · Full text

Life Sciences, Immunology, Molecular Biology +13