Lane A. Clizbe

Discovery of betrixaban (PRT054021), N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide, a highly potent, selective, and orally efficacious factor Xa inhibitor

Penglie Zhang, Wenrong Huang, Lingyan Wang et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 105 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +10

Diels-Alder reactions of 1-(acylamino)-1,3-dienes

Larry E. Overman, Robert L. Freerks, C. B. PETTY et al. · Journal of the American Chemical Society · 1981 · 67 citations

Molecular Sciences, Engineering, Alkene Metathesis +13

Synthesis of trichloroacetamido-1,3-dienes. Useful aminobutadiene equivalents for the Diels-Alder reaction

Larry E. Overman, Lane A. Clizbe · Journal of the American Chemical Society · 1976 · 65 citations

Combinatorial Chemistry, Halogenation, Chemical Measurement +11

Thermal rearrangements of propargylic trichloroacetimidates. Synthesis of (trichloroacetamido)-1,3-dienes and -1,2-dienes

Larry E. Overman, Lane A. Clizbe, Robert L. Freerks et al. · Journal of the American Chemical Society · 1981 · 57 citations

-1,2-Dieneslarry E. Overman, Chemical Engineering, Engineering +9

A simple synthesis of L-.gamma.-carboxyglutamate and derivatives thereof

Samuel J. Danishefsky, Ellen Berman, Lane A. Clizbe et al. · Journal of the American Chemical Society · 1979 · 50 citations

Ellen Berman, Derivatives, Chemical Analysis +14