Alec R. Chapman

Genome-Wide Detection of Single-Nucleotide and Copy-Number Variations of a Single Human Cell

Chenghang Zong, Sijia Lü, Alec R. Chapman et al. · Science · 2012 · 1.2K citations · Full text

Copy-number Variations, Genetics, Molecular Genetics +19

Single-molecule imaging of transcription factor binding to DNA in live mammalian cells

J. Christof M. Gebhardt, David M. Suter, Rahul Roy et al. · Nature Methods · 2013 · 535 citations · Full text

Chromatin, Transcriptional Regulation, Novel Imaging Method +11

Reproducible copy number variation patterns among single circulating tumor cells of lung cancer patients

Xiaohui Ni, Minglei Zhuo, Zhe Su et al. · Proceedings of the National Academy of Sciences · 2013 · 477 citations · Full text

Probing Meiotic Recombination and Aneuploidy of Single Sperm Cells by Whole-Genome Sequencing

Sijia Lü, Chenghang Zong, Wei Fan et al. · Science · 2012 · 303 citations · Full text

Cytogenetics, Genetics, Single Sperm Cells +21

Spatial organization of RNA polymerase II inside a mammalian cell nucleus revealed by reflected light-sheet superresolution microscopy

Ziqing Zhao, Rahul Roy, J. Christof M. Gebhardt et al. · Proceedings of the National Academy of Sciences · 2013 · 145 citations · Full text