Alec R. Chapman

Genome-Wide Detection of Single-Nucleotide and Copy-Number Variations of a Single Human Cell

Chenghang Zong, Sijia Lü, Alec R. Chapman et al. · Science · 2012 · 1.2K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Single-molecule imaging of transcription factor binding to DNA in live mammalian cells

J. Christof M. Gebhardt, David M. Suter, Rahul Roy et al. · Nature Methods · 2013 · 546 citations · Full text

Natural Sciences, Cell Biology, Molecular Biology +15

Reproducible copy number variation patterns among single circulating tumor cells of lung cancer patients

Xiaohui Ni, Minglei Zhuo, Zhe Su et al. · Proceedings of the National Academy of Sciences · 2013 · 481 citations · Full text

Medicine, Genetics, Oncology +17

Probing Meiotic Recombination and Aneuploidy of Single Sperm Cells by Whole-Genome Sequencing

Sijia Lü, Chenghang Zong, Wei Fan et al. · Science · 2012 · 310 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15

Spatial organization of RNA polymerase II inside a mammalian cell nucleus revealed by reflected light-sheet superresolution microscopy

Ziqing Zhao, Rahul Roy, J. Christof M. Gebhardt et al. · Proceedings of the National Academy of Sciences · 2013 · 149 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17