Haematopoietic stem and progenitor cells from human pluripotent stem cells

Ryohichi Sugimura, Deepak Kumar Jha, Areum Han, +16

Nature

YAP Regulates Hematopoietic Stem Cell Formation in Response to the Biomechanical Forces of Blood Flow

Vanessa Lundin, Wade W. Sugden, Lindsay N. Theodore, +9

Developmental Cell

MechanobiologyBiomechanical ForcesMedicineStem Cell MobilizationPhysiology +10

Regulation of embryonic haematopoietic multipotency by EZH1

Linda T. Vo, Melissa A. Kinney, Xin Liu, +12

Nature

Cell LineageDevelopmental BiologyCell DivisionMorphogenesisEmbryonic Haematopoietic Multipotency +4

A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development

Marcella Cesana, Michael H. Guo, Davide Cacchiarelli, +18

Cell stem cell

Lineage PlasticityDevelopmental BiologyMedicineStem Cell MobilizationStem Cell Research +4

The Lin28/let-7 Pathway Regulates the Mammalian Caudal Body Axis Elongation Program

Daisy A. Robinton, Jérome Chal, Edroaldo Lummertz da Rocha, +9

Developmental Cell

Developmental BiologySignaling PathwayCell RegulationCell SignalingDevelopmental Genetics +7

Developmental regulation of myeloerythroid progenitor function by the <i>Lin28b</i>–<i>let-7</i>–<i>Hmga2</i> axis

R. Grant Rowe, Leo D. Wang, Sílvia Coma, +9

The Journal of Experimental Medicine

GeneticsImmunologyBlood CellEpigeneticsCellular Physiology +17

Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis

Alena Yermalovich, Jihan K. Osborne, Patricia Sousa, +10

Nature Communications

The developmental stage of the hematopoietic niche regulates lineage in <i>MLL-</i>rearranged leukemia

R. Grant Rowe, Edroaldo Lummertz da Rocha, Patricia Sousa, +10

The Journal of Experimental Medicine

Engineered Murine HSCs Reconstitute Multi-lineage Hematopoiesis and Adaptive Immunity

Yi-Fen Lu, Patrick Cahan, Samantha Ross, +8

Cell Reports

EDIT-301: An Experimental Autologous Cell Therapy Comprising Cas12a-RNP Modified mPB-CD34+ Cells for the Potential Treatment of SCD

Edouard De Dreuzy, Jack Heath, John A. Zuris, +13

Blood