Tomohiko Tasaka

Design and Synthesis of DDR1 Inhibitors with a Desired Pharmacophore Using Deep Generative Models

Atsushi Yoshimori, Yasunobu Asawa, Enzo Kawasaki et al. · ChemMedChem · 2020 · 42 citations · Full text

Strategies for Design of Molecular Structures with a Desired Pharmacophore Using Deep Reinforcement Learning

Atsushi Yoshimori, Enzo Kawasaki, Chisato Kanai et al. · Chemical and Pharmaceutical Bulletin · 2020 · 32 citations · Full text

Drug Target, Engineering, Machine Learning +20

<i>N</i>-Benzoyl-1,5-benzothiazepine and Its<i>S</i>-Oxide as Vasopressin Receptor Ligands: Insight into the Active Stereochemistry around the Seven-Membered Ring

Tetsuya Yoneda, Hidetsugu Tabata, Tomohiko Tasaka et al. · Journal of Medicinal Chemistry · 2015 · 30 citations · Full text

<i>N</i>-Benzoyl- and <i>N</i>-Sulfonyl-1,5-benzodiazepines: Comparison of Their Atropisomeric and Conformational Properties

Tetsuya Yoneda, Hidetsugu Tabata, Jun Nakagomi et al. · The Journal of Organic Chemistry · 2014 · 29 citations

RAISING is a high-performance method for identifying random transgene integration sites

Yusaku Wada, Tomoo Sato, Hiroo Hasegawa et al. · Communications Biology · 2022 · 29 citations · Full text