Concepedia

Chris D. Pacheco

CD

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Publications

5

Citations

567

H-Index

5

Active since

2007

Affiliations

University of Michigan(Current)

Society for Neuroscience

National Student Clearinghouse Research Center

Chris D. Pacheco is an author at University of Michigan specializing in molecular neuroscience, lysosomal storage disease, and neuroprotection.

Top concepts

Publications per year

2007–2012

5

Publications

5

Autophagy in Niemann–Pick C disease is dependent upon Beclin-1 and responsive to lipid trafficking defects

Chris D. Pacheco, Robin Kunkel, Andrew P. Lieberman · Human Molecular Genetics · 2007 · 200 citations · Full text

Conditional Niemann-Pick C mice demonstrate cell autonomous Purkinje cell neurodegeneration

Matthew J. Elrick, Chris D. Pacheco, Ting Yu et al. · Human Molecular Genetics · 2009 · 140 citations · Full text

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Conserved features of intermediates in amyloid assembly determine their benign or toxic states

Rajaraman Krishnan, Jessica L. Goodman, Samrat Mukhopadhyay et al. · Proceedings of the National Academy of Sciences · 2012 · 131 citations · Full text

Tau deletion exacerbates the phenotype of Niemann–Pick type C mice and implicates autophagy in pathogenesis

Chris D. Pacheco, Matthew J. Elrick, Andrew P. Lieberman · Human Molecular Genetics · 2008 · 74 citations · Full text

Tau normal function influences Niemann-Pick type C disease pathogenesis in mice and modulates autophagy in NPC1-deficient cells

Chris D. Pacheco, Matthew J. Elrick, Andrew P. Lieberman · Autophagy · 2009 · 22 citations · Full text

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