Irit Lax

Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin

Towia A. Libermann, Harris R. Nusbaum, Nissim Razon et al. · Nature · 1985 · 1.5K citations

Medicine, Molecular Genetics, Oncology +12

A Lipid-Anchored Grb2-Binding Protein That Links FGF-Receptor Activation to the Ras/MAPK Signaling Pathway

Haruhiko Kouhara, Yaron R. Hadari, Taly R. Spivak-Kroizman et al. · Cell · 1997 · 871 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Heparin-induced oligomerization of FGF molecules is responsible for FGF receptor dimerization, activation, and cell proliferation

Taly R. Spivak-Kroizman, Mark A. Lemmon, John E. Ladbury et al. · Cell · 1994 · 662 citations

Life Sciences, Biochemistry, Molecular Biology +14

FRS2 Proteins Recruit Intracellular Signaling Pathways by Binding to Diverse Targets on Fibroblast Growth Factor and Nerve Growth Factor Receptors

S.H. Ong, Graeme R. Guy, Yaron R. Hadari et al. · Molecular and Cellular Biology · 2000 · 363 citations

Life Sciences, Biochemistry, Molecular Biology +15

Structure of a heparin-linked biologically active dimer of fibroblast growth factor

Anna D. DiGabriele, Irit Lax, Denise I. Chen et al. · Nature · 1998 · 357 citations

Life Sciences, Biology, Molecular Biology +11