Tijun Wu

M1 macrophage-derived exosomes impair beta cell insulin secretion via miR-212-5p by targeting SIRT2 and inhibiting Akt/GSK-3β/β-catenin pathway in mice

Bin Qian, Yang� Yang, Ningyuan Tang et al. · Diabetologia · 2021 · 86 citations · Full text

Signal Transduction, Signaling Pathway, Immunology +7

HRD1, an Important Player in Pancreatic β-Cell Failure and Therapeutic Target for Type 2 Diabetic Mice

Tijun Wu, Shuang Zhang, Jialiang Xu et al. · Diabetes · 2020 · 58 citations · Full text

Ets1-Mediated Acetylation of FoxO1 Is Critical for Gluconeogenesis Regulation during Feed-Fast Cycles

Kai Li, Chen Qiu, Peng Sun et al. · Cell Reports · 2019 · 57 citations · Full text

Glucose Homeostasis, Gluconeogenesis Regulation, Metabolic Remodeling +20

NR3C1/Glucocorticoid receptor activation promotes pancreatic β-cell autophagy overload in response to glucolipotoxicity

Tijun Wu, Yixue Shao, Xirui Li et al. · Autophagy · 2023 · 51 citations · Full text

Transcription factor Ets-1 links glucotoxicity to pancreatic beta cell dysfunction through inhibiting PDX-1 expression in rodent models

Fang Chen, Min Sha, Yanyang Wang et al. · Diabetologia · 2015 · 50 citations · Full text

Inflammation, Signal Transduction, Signaling Pathway +11