Larry Murphy

Amidinohydrazones as guanidine bioisosteres: application to a new class of potent, selective and orally bioavailable, non-amide-based small-molecule thrombin inhibitors

Richard Söll, Tianobao Lu, Bruce E. Tomczuk et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 38 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Pharmaceutical Science +11

Oxyguanidines: application to non-peptidic phenyl-based thrombin inhibitors

Bruce E. Tomczuk, Tianbao Lu, Richard Söll et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 30 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +5

In vitro evaluation and crystallographic analysis of a new class of selective, non-amide-based thrombin inhibitors

Tianbao Lu, Bruce E. Tomczuk, Carl R. Illig et al. · Bioorganic & Medicinal Chemistry Letters · 1998 · 24 citations · Full text

Thrombosis, Medicinal Chemistry, Biochemistry +11

Structure–activity and crystallographic analysis of a new class of non-amide-based thrombin inhibitor

Tianbao Lu, Richard Söll, Carl R. Illig et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 15 citations · Full text

Molecular Docking, Non-amide-based Thrombin Inhibitor, Biochemistry +7

Non-peptidic phenyl-Based thrombin inhibitors: exploring structural requirements of the S1 specificity pocket with amidines

Tianbao Lu, Bruce E. Tomczuk, Roger Bone et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 12 citations · Full text

Medicinal Chemistry, Drug Target, Biochemistry +11