Concepedia

Simon Chivers

SC

14

Publications

644

Citations

11

H-Index

2013

Active since

Affiliations

Spirogen (United Kingdom)(Current)

University College London

Novartis (Switzerland)

Adc Therapeutics (Switzerland)

AstraZeneca (United Kingdom)

Simon Chivers is an author at Spirogen (United Kingdom) specializing in medicine, pharmacology, and drug discovery.

ORCID

Top concepts

Publications per year

2013–2024

14

Publications

14

ADCT-402, a PBD dimer–containing antibody drug conjugate targeting CD19-expressing malignancies

Francesca Zammarchi, Simon Corbett, Lauren Adams et al. · Blood · 2018 · 174 citations · Full text

Pre-clinical pharmacology and mechanism of action of SG3199, the pyrrolobenzodiazepine (PBD) dimer warhead component of antibody-drug conjugate (ADC) payload tesirine

John A. Hartley, Michael Flynn, John P. Bingham et al. · Scientific Reports · 2018 · 123 citations · Full text

CD25-targeted antibody–drug conjugate depletes regulatory T cells and eliminates established syngeneic tumors via antitumor immunity

Francesca Zammarchi, Karin Havenith, François Bertelli et al. · Journal for ImmunoTherapy of Cancer · 2020 · 77 citations · Full text

Efficacy of anti-sclerostin monoclonal antibody BPS804 in adult patients with hypophosphatasia

Lothar Seefried, Jasmin Baumann, Sarah Hemsley et al. · Journal of Clinical Investigation · 2017 · 74 citations · Full text

Placental Transfer of Fc‐Containing Biopharmaceuticals across Species, an Industry Survey Analysis

Christopher Bowman, William J. Breslin, Anu Connor et al. · Birth Defects Research Part B Developmental and Reproductive Toxicology · 2013 · 50 citations · Full text

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