Alexander Paasche

Evidence for Substrate Binding-Induced Zwitterion Formation in the Catalytic Cys-His Dyad of the SARS-CoV Main Protease

Alexander Paasche, Andreas Zipper, Simon T. Schafer et al. · Biochemistry · 2014 · 104 citations

Protein Assembly, Sars-cov Main Protease, Molecular Biology +19

Benchmark Study for the Cysteine–Histidine Proton Transfer Reaction in a Protein Environment: Gas Phase, COSMO, QM/MM Approaches

Alexander Paasche, Tanja Schirmeister, Bernd Engels · Journal of Chemical Theory and Computation · 2013 · 56 citations

Protein Chemistry, Biochemistry, Gas Phase +13

Mechanistic Study of the Reaction of Thiol‐Containing Enzymes with α,β‐Unsaturated Carbonyl Substrates by Computation and Chemoassays

Alexander Paasche, Markus Schiller, Tanja Schirmeister et al. · ChemMedChem · 2010 · 38 citations · Full text

Origin of the Reactivity Differences of Substituted Aziridines: CN vs CC Bond Breakages

Alexander Paasche, Mario Arnone, Reinhold F. Fink et al. · The Journal of Organic Chemistry · 2009 · 33 citations

Combinatorial Chemistry, Substitution Patterns, Chemical Transformation +16

A Flexible Route to Chiral 2-<i>endo</i>-Substituted 9-Oxabispidines and Their Application in the Enantioselective Oxidation of Secondary Alcohols

Matthias Breuning, Melanie Steiner, Christian Mehler et al. · The Journal of Organic Chemistry · 2008 · 32 citations

Excellent Selectivity Factors, Chemical Engineering, Engineering +11