John Mallon

Real-time observation of DNA target interrogation and product release by the RNA-guided endonuclease CRISPR Cpf1 (Cas12a)

Digvijay Singh, John Mallon, Anustup Poddar et al. · Proceedings of the National Academy of Sciences · 2018 · 215 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +10

Mechanisms of improved specificity of engineered Cas9s revealed by single-molecule FRET analysis

Digvijay Singh, Yanbo Wang, John Mallon et al. · Nature Structural & Molecular Biology · 2018 · 135 citations

Life Sciences, Biotechnology, Molecular Biology +10

Alterations in Circulating Vitamin D Metabolites in the Young Insulin-Dependent Diabetic*

Teresa Frazer, Neil H. White, Stephen Hough et al. · The Journal of Clinical Endocrinology & Metabolism · 1981 · 110 citations

Medicine, Endocrinology, Bone Metabolism +16

An improved competitive protein binding assay for 1,25-dihydroxyvitamin D

John Mallon, James G. Hamilton, Cheryl Nauss-Karol et al. · Archives of Biochemistry and Biophysics · 1980 · 55 citations

Medicine, Biochemistry, Pharmacology +10

Single molecule analysis of effects of non-canonical guide RNAs and specificity-enhancing mutations on Cas9-induced DNA unwinding

Ikenna C. Okafor, Digvijay Singh, Yanbo Wang et al. · Nucleic Acids Research · 2019 · 54 citations · Full text

Life Sciences, Genetics, Molecular Biology +9