Matthew R. Strickland

Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells

Robin M. Meyers, Jordan Bryan, James M. McFarland et al. · Nature Genetics · 2017 · 2.1K citations · Full text

Genetics, Genetic Engineering, Crispr–cas9 Essentiality Screens +7

Genomic characterization of human brain metastases identifies drivers of metastatic lung adenocarcinoma

David Shih, Naema Nayyar, Ivanna V. Bihun et al. · Nature Genetics · 2020 · 292 citations · Full text

Tumor Heterogeneity, Medicine, Metastatic Lung Adenocarcinoma +10

Cancer Vulnerabilities Unveiled by Genomic Loss

Deepak Nijhawan, Travis Zack, Yin Ren et al. · Cell · 2012 · 236 citations · Full text

Genome Instability, Medicine, Genetics +5

PRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling

Susan E. Moody, Anna C. Schinzel, Sharat Singh et al. · Oncogene · 2014 · 115 citations · Full text

Breast Oncology, Her2-targeted Therapy, Medicine +8

Activity of Adagrasib (MRTX849) in Brain Metastases: Preclinical Models and Clinical Data from Patients with KRASG12C-Mutant Non–Small Cell Lung Cancer

Joshua K. Sabari, Vamsidhar Velcheti, K. Shimizu et al. · Clinical Cancer Research · 2022 · 115 citations · Full text