Tammy Watchorn

Oxidant-mediated lung epithelial cell tolerance: the role of intracellular glutathione and nuclear factor-kappaB 1 1Abbreviations: A549 cells, human alveolar epithelial type II cell line; AP-1, activator protein-1; BSO; dl-buthionine (SR)-sulfoximine; COPD, chronic obstructive pulmonary disease; DMEM, Dulbecco’s modified Eagle’s medium; DTT, dithiothreitol; GSHMEE, glutathione monoethyl ester; H2O2, hydrogen peroxide; IkB, inhibitory binding protein kB; LDH, lactic dehydrogenase; NAC, N-acetyl-l-cysteine; NF-kB, nuclear factor-kappa b; NPSH, non-protein sulphydryls; PKC, protein kinase C; and ROS, reactive oxygen species.

Irfan Rahman, Brigitte Mulier, Peter S. Gilmour et al. · Biochemical Pharmacology · 2001 · 130 citations

Life Sciences, Cell Biology, Pharmacology +17

Proteolysis‐inducing factor regulates hepatic gene expression via the transcription factors NF‐κΒ and STAT3

Tammy Watchorn, Ian D. Waddell, Nabil Dowidar et al. · The FASEB Journal · 2001 · 101 citations

Life Sciences, Cell Biology, Molecular Biology +15

Hydrogen peroxide-induced epithelial injury: the protective role of intracellular nonprotein thiols (NPSH)

Brigitte Mulier, Irfan Rahman, Tammy Watchorn et al. · European Respiratory Journal · 1998 · 84 citations · Full text

Life Sciences, Cell Biology, Toxicology +17

Proteolysis-inducing factor differentially influences transcriptional regulation in endothelial subtypes

Tammy Watchorn, Ian D. Waddell, J. A. Ross · American Journal of Physiology-Endocrinology and Metabolism · 2002 · 30 citations

Life Sciences, Cell Biology, Molecular Biology +13

The cachectic mediator proteolysis inducing factor activates NF-κB and STAT3 in human Kupffer cells and monocytes

Tammy Watchorn, Nabil Dowidar, Cornelis H.C. Dejong et al. · International Journal of Oncology · 2005 · 28 citations

Life Sciences, Cell Biology, Immunology +17