Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT

Gianluca Baldanzi, Nicoletta Filigheddu, Santina Cutrupi, +17

The Journal of Cell Biology

Optogenetic control of heart muscle in vitro and in vivo

Tobias Bruegmann, Daniela Malan, Michael Hesse, +4

Nature Methods

Heart MuscleCardiac MuscleCardiomyopathyMedicinePhysiology +9

Macrophage-dependent IL-1β production induces cardiac arrhythmias in diabetic mice

Gustavo Monnerat, Micaela López Alarcón, Luiz Ricardo C. Vasconcellos, +16

Nature Communications

Cardiac effects of ghrelin and its endogenous derivatives des-octanoyl ghrelin and des-Gln14-ghrelin

Ivano Bedendi, Giuseppe Alloatti, Andrea Marcantoni, +6

European Journal of Pharmacology

Heart FailureBiochemistryCardiac EffectsMedicinePhysiology +4

Cardiomyocytes Obtained From Induced Pluripotent Stem Cells With Long-QT Syndrome 3 Recapitulate Typical Disease-Specific Features In Vitro

Daniela Malan, Stephanie Friedrichs, Bernd K. Fleischmann, +1

Circulation Research

Modulation of Calcium-Activated Potassium Channels Induces Cardiogenesis of Pluripotent Stem Cells and Enrichment of Pacemaker-Like Cells

Alexander Kleger, Thomas Seufferlein, Daniela Malan, +22

Circulation

Systemic gene transfer enables optogenetic pacing of mouse hearts

C Vogt, Tobias Bruegmann, Daniela Malan, +4

Cardiovascular Research

Human iPS cell model of type 3 long QT syndrome recapitulates drug-based phenotype correction

Daniela Malan, Miao Zhang, Birgit Stallmeyer, +5

Basic Research in Cardiology

Universal Cardiac Induction of Human Pluripotent Stem Cells in Two and Three-Dimensional Formats: Implications for In Vitro Maturation

Miao Zhang, Jan S. Schulte, Alexander Heinick, +15

Stem Cells

Tissue EngineeringCardiac MuscleEngineeringAdult Stem CellCardiac Progenitor Cells +21

Deletion of the last five C-terminal amino acid residues of connexin43 leads to lethal ventricular arrhythmias in mice without affecting coupling via gap junction channels

Indra Lübkemeier, Robert Pascal Requardt, Xianming Lin, +15

Basic Research in Cardiology

Gap Junction ChannelsMolecular PharmacologyVentricular ArrhythmiasCardiomyopathyMolecular Physiology +9