Jason C. McCoy

Structural basis for potency differences between GDF8 and GDF11

Ryan G. Walker, Magdalena Czepnik, Erich J. Goebel et al. · BMC Biology · 2017 · 118 citations · Full text

Structure of the human myostatin precursor and determinants of growth factor latency

Thomas R. Cotton, Gerhard W. Fischer, Xuelu Wang et al. · The EMBO Journal · 2018 · 68 citations · Full text

Developmental Biology, Molecular Physiology, Growth Hormone +7

Molecular characterization of latent GDF8 reveals mechanisms of activation

Ryan G. Walker, Jason C. McCoy, Magdalena Czepnik et al. · Proceedings of the National Academy of Sciences · 2018 · 36 citations · Full text

Molecular Regulation, Mechanotransduction, Cellular Physiology +16

Mutations in GDF11 and the extracellular antagonist, Follistatin, as a likely cause of Mendelian forms of orofacial clefting in humans

Timothy C. Cox, Andrew C. Lidral, Jason C. McCoy et al. · Human Mutation · 2019 · 31 citations · Full text

Gdf11 Antagonist, Extracellular Antagonist, Genetics +19

Crystal structure of the WFIKKN2 follistatin domain reveals insight into how it inhibits growth differentiation factor 8 (GDF8) and GDF11

Jason C. McCoy, Ryan G. Walker, Nathan H. Murray et al. · Journal of Biological Chemistry · 2019 · 16 citations · Full text

Skeletal Muscle Growth, Crystal Structure, Protein Function +13