Lidan Hu

Lanosterol reverses protein aggregation in cataracts

Ling Zhao, Xiangjun Chen, Jie Zhu et al. · Nature · 2015 · 439 citations

Protein Function, Oxysterol, Biochemistry +5

Lanosterol and 25-hydroxycholesterol dissociate crystallin aggregates isolated from cataractous human lens via different mechanisms

Xiangjun Chen, Lidan Hu, Ke Yao et al. · Biochemical and Biophysical Research Communications · 2018 · 48 citations

Pharmacology, Different Mechanisms, Oxysterol +1

ATP-mediated protein kinase B Akt/mammalian target of rapamycin mTOR/p70 ribosomal S6 protein p70S6 kinase signaling pathway activation promotes improvement of locomotor function after spinal cord injury in rats

Lidan Hu, Z.G. Sun, Yimin Wen et al. · Neuroscience · 2010 · 44 citations

Molecular Neuroscience, Molecular Physiology, Kinesiology +10

Cataract-causing mutation S228P promotes βB1-crystallin aggregation and degradation by separating two interacting loops in C-terminal domain

Liangbo Qi, Lidan Hu, Huihui Liu et al. · Protein & Cell · 2016 · 39 citations · Full text

Protein Assembly, S228p Mutation, Molecular Biology +16

Lanosterol modulates proteostasis via dissolving cytosolic sequestosomes/aggresome-like induced structures

Lidan Hu, Jing Wang, Xiangjun Chen et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 2019 · 27 citations

Signal Transduction, Oxysterol, Cytosolic Sequestosomes/aggresome-like +4