Gerjon J. Ikink

RSPO3 expands intestinal stem cell and niche compartments and drives tumorigenesis

John Hilkens, Nikki C Timmer, Mandy Boer et al. · Gut · 2016 · 82 citations · Full text

IRS4 induces mammary tumorigenesis and confers resistance to HER2-targeted therapy through constitutive PI3K/AKT-pathway hyperactivation

Gerjon J. Ikink, Mandy Boer, Elvira R. M. Bakker et al. · Nature Communications · 2016 · 66 citations · Full text

Insulin receptor substrate 4 (IRS4) is a constitutive active oncogenic driver collaborating with HER2 and causing therapeutic resistance

Gerjon J. Ikink, John Hilkens · Molecular & Cellular Oncology · 2017 · 20 citations · Full text

Insulin Signaling, Upstream Signals, Metabolic Syndrome +17

Insertional mutagenesis in a HER2-positive breast cancer model reveals ERAS as a driver of cancer and therapy resistance

Gerjon J. Ikink, Mandy Boer, Elvira R. M. Bakker et al. · Oncogene · 2018 · 10 citations · Full text

Her2+ Breast Cancer, Systems Biology, Breast Oncology +15