Grainne M. O’Kane

Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer

Hervé Tiriac, Pascal Belleau, Dannielle D. Engle et al. · Cancer Discovery · 2018 · 1.1K citations · Full text

Medicine, Cancer Biology, Oncology +17

Sensitive tumour detection and classification using plasma cell-free DNA methylomes

Shu Yi Shen, Rajat Singhania, Gordon Fehringer et al. · Nature · 2018 · 1K citations · Full text

Medicine, Molecular Biology, Oncology +14

Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity

Kebria Hezaveh, Rahul Shinde, Andreas Klötgen et al. · Immunity · 2022 · 692 citations · Full text

Life Sciences, Immunology, Oncology +17

Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution

Michelle Chan‐Seng‐Yue, Jaeseung Kim, Gavin W. Wilson et al. · Nature Genetics · 2020 · 689 citations · Full text

Medicine, Molecular Biology, Oncology +17

Genomics-Driven Precision Medicine for Advanced Pancreatic Cancer: Early Results from the COMPASS Trial

Kyaw Aung, Sandra E. Fischer, Robert E. Denroche et al. · Clinical Cancer Research · 2017 · 636 citations · Full text

Medicine, Molecular Medicine, Oncology +17