Different enantioselective 9-hydroxylation of risperidone by the two human CYP2D6 and CYP3A4 enzymes.

Norio Yasui‐Furukori, Mats Hidestrand, Edoardo Spina, +3

PubMed

Pharmaceutical SciencePharmacotherapyChemical BiologyExperimental PharmacologyPharmaceutical Chemistry +18

Role of CYP2C9 polymorphism in losartan oxidation.

Ümit Yaşar, Gunnel Tybring, Mats Hidestrand, +4

PubMed

Molecular BiologyMolecular GeneticsPharmacotherapyIntrinsic ClearanceRedox Biology +15

A Combination of Mutations in the CYP2D6*17(CYP2D6Z) Allele Causes Alterations in Enzyme Function

Mikael Oscarson, Mats Hidestrand, Inger Johansson, +1

Molecular Pharmacology

Functional Analysis of Six Different Polymorphic CYP1B1 Enzyme Variants Found in an Ethiopian Population

Eleni Aklillu, Mikael Oscarson, Mats Hidestrand, +3

Molecular Pharmacology

Cytochrome P 450 isoforms involved in melatonin metabolism in human liver microsomes

Gabriella Facciolà, Mats Hidestrand, Christer von Bahr, +1

European Journal of Clinical Pharmacology

Cytochrome P 450Melatonin MetabolismBiochemistryMedicineLiver Physiology +8

Human gene copy number spectra analysis in congenital heart malformations

Aoy Tomita‐Mitchell, Donna K. Mahnke, Craig A. Struble, +11

Physiological Genomics

Cardiometabolic RiskGeneticsGenetic EpidemiologyCongenital Heart MalformationsMolecular Genetics +25

Donor fraction cell-free DNA and rejection in adult and pediatric heart transplantation

Marc E. Richmond, Steven Zangwill, Steven J. Kindel, +14

The Journal of Heart and Lung Transplantation

CYP2B6 and CYP2C19 as the major enzymes responsible for the metabolism of selegiline, a drug used in the treatment of Parkinson's disease, as revealed from experiments with recombinant enzymes.

Mats Hidestrand, Mikael Oscarson, Jarmo S. Salonen, +4

PubMed

Selegiline ClearanceAldehyde DehydrogenaseBiochemistryMedicineMajor Enzymes +11

Identification of CYP4F8 in Human Seminal Vesicles as a Prominent 19-Hydroxylase of Prostaglandin Endoperoxides

Johan Bylund, Mats Hidestrand, Magnus Ingelman‐Sundberg, +1

Journal of Biological Chemistry

AndrologyOxysterolBiochemistryNatural SciencesMedicine +11

Impact of <i>MYH6</i> variants in hypoplastic left heart syndrome

Aoy Tomita‐Mitchell, Karl Stamm, Donna K. Mahnke, +11

Physiological Genomics