Icariin, a phoshphodiesterase-5 inhibitor, improves learning and memory in APP/PS1 transgenic mice by stimulation of NO/cGMP signalling

Feng Jin, Qihai Gong, Ya-Sha Xu, +6

The International Journal of Neuropsychopharmacology

Nitric OxideNeurotransmitterNeurochemical BiomarkersAmyloid Precursor ProteinSynaptic Signaling +16

The P2Y2 Nucleotide Receptor Mediates the Proliferation and Migration of Human Hepatocellular Carcinoma Cells Induced by ATP

Rui Xie, Jingyu Xu, Guorong Wen, +8

Journal of Biological Chemistry

Cancer BiologyTumor BiologyCancer Cell BiologyAtp ActionCell Signaling +14

Serum Metabolomic Signatures of Lymph Node Metastasis of Esophageal Squamous Cell Carcinoma

Hai Jin, Fan Qiao, Ling Chen, +3

Journal of Proteome Research

Esophageal CancerChemoprevention StrategySerum Metabolomic SignaturesMetabolomic ProfilingPathology +19

Expression and functional role of vacuolar H+-ATPase in human hepatocellular carcinoma

Jingyu Xu, Rui Xie, Xingguang Liu, +9

Carcinogenesis

Human Hepatocellular CarcinomaFunctional RoleTumor CellsCellular PhysiologyTumor Biology +14

Six Novel Biomarkers for Diagnosis and Prognosis of Esophageal squamous cell carcinoma: validated by scRNA-seq and qPCR

Liuhai Zheng, Linzhi Li, Jun Xie, +2

Journal of Cancer

Decreased expression of microRNA-320a promotes proliferation and invasion of non-small cell lung cancer cells by increasing VDAC1 expression

Guanxin Zhang, Chong Wang, Keng Zhong, +5

Oncotarget

Nsclc TissuesPathologyVdac1 ExpressionCancer BiologyTumor Biology +14

Ubiquitin-specific protease 2a stabilizes MDM4 and facilitates the p53-mediated intrinsic apoptotic pathway in glioblastoma

Chunlin Wang, Junyu Wang, Zhenyang Liu, +7

Carcinogenesis

Kaempferol inhibits cell proliferation and glycolysis in esophagus squamous cell carcinoma via targeting EGFR signaling pathway

Shihua Yao, Xiaowei Wang, Chunguang Li, +3

Tumor Biology

The NCX1/TRPC6 Complex Mediates TGFβ-Driven Migration and Invasion of Human Hepatocellular Carcinoma Cells

Jingyu Xu, Yuan Yang, Rui Xie, +7

Cancer Research

Resveratrol delays 6-hydroxydopamine-induced apoptosis by activating the PI3K/Akt signaling pathway

Nanqu Huang, Ying Zhang, Mingji Chen, +6

Experimental Gerontology

Reductive StressChemoprevention StrategyMedicineApoptosisAutophagy +7