D J Lew

Cytoplasmic activation of GAF, an IFN-gamma-regulated DNA-binding factor.

Thomas Decker, D J Lew, Jovan Mirkovitch et al. · The EMBO Journal · 1991 · 380 citations · Full text

Transcriptional Regulation, Cell Regulation, Molecular Regulation +6

Overlapping elements in the guanylate-binding protein gene promoter mediate transcriptional induction by alpha and gamma interferons.

D J Lew, Thomas Decker, Inga Strehlow et al. · Molecular and Cellular Biology · 1991 · 272 citations · Full text

Molecular Regulation, Genetics, Molecular Biology +19

Synergistic interaction between interferon-alpha and interferon-gamma through induced synthesis of one subunit of the transcription factor ISGF3.

David T. Levy, D J Lew, Thomas Decker et al. · The EMBO Journal · 1990 · 218 citations · Full text

Transcriptional Regulation, Systems Biology, Signal Transduction +11

Interactions of alpha- and gamma-interferon in the transcriptional regulation of the gene encoding a guanylate-binding protein.

Thomas Decker, D J Lew, Yuxiang Cheng et al. · The EMBO Journal · 1989 · 163 citations · Full text

Transcriptional Regulation, Systems Biology, Natural Sciences +9

Two distinct alpha-interferon-dependent signal transduction pathways may contribute to activation of transcription of the guanylate-binding protein gene.

Thomas Decker, D J Lew, James Darnell · Molecular and Cellular Biology · 1991 · 131 citations · Full text

Rapid Activation, Genetics, Ifn-alpha Activation Factor +18