Brice E. Uno

Amphotericin primarily kills yeast by simply binding ergosterol

Kaitlyn Gray, Daniel S. Palacios, Ian Dailey et al. · Proceedings of the National Academy of Sciences · 2012 · 584 citations · Full text

Amphotericin forms an extramembranous and fungicidal sterol sponge

Thomas M. Anderson, Mary C. Clay, Alexander G. Cioffi et al. · Nature Chemical Biology · 2014 · 496 citations · Full text

Biosynthesis, Antifungal Agent, Medicine +4

Vinyl MIDA boronate: a readily accessible and highly versatile building block for small molecule synthesis

Brice E. Uno, Eric P. Gillis, Martin D. Burke · Tetrahedron · 2008 · 143 citations

Versatile Building Block, Engineering, Organic Chemistry +8

C2′-OH of Amphotericin B Plays an Important Role in Binding the Primary Sterol of Human Cells but Not Yeast Cells

Brandon C. Wilcock, Matthew M. Endo, Brice E. Uno et al. · Journal of the American Chemical Society · 2013 · 107 citations · Full text

Pharmaceutical Science, Fungal Cell Biology, Yeast Cells +20

Tuning sterol extraction kinetics yields a renal-sparing polyene antifungal

Arun Maji, Corinne P. Soutar, Jiabao Zhang et al. · Nature · 2023 · 82 citations · Full text