Sarah Howat

Endothelin-1 Induces Expression of Matrix-associated Genes in Lung Fibroblasts through MEK/ERK

Shiwen Xu, Sarah Howat, Elisabetta Renzoni et al. · Journal of Biological Chemistry · 2004 · 169 citations · Full text

Constitutive ALK5-Independent c-Jun N-Terminal Kinase Activation Contributes to Endothelin-1 Overexpression in Pulmonary Fibrosis: Evidence of an Autocrine Endothelin Loop Operating through the Endothelin A and B Receptors

Shiwen Xu, Fernando Rodrı́guez-Pascual, Santiago Lamas et al. · Molecular and Cellular Biology · 2006 · 153 citations · Full text

Lung Inflammation, Immunology, Endothelin A +20

CCN2 Is Necessary for Adhesive Responses to Transforming Growth Factor-β1 in Embryonic Fibroblasts

Shiwen Xu, Lee Anne Stanton, Laura Kennedy et al. · Journal of Biological Chemistry · 2006 · 149 citations · Full text

An Essential Role for Resident Fibroblasts in Experimental Lung Fibrosis Is Defined by Lineage-Specific Deletion of High-Affinity Type II Transforming Growth Factor β Receptor

Rachel K. Hoyles, Emma Derrett‐Smith, Korsa Khan et al. · American Journal of Respiratory and Critical Care Medicine · 2010 · 132 citations

TRPV1 Deletion Enhances Local Inflammation and Accelerates the Onset of Systemic Inflammatory Response Syndrome

Elizabeth S. Fernandes, Lihuan Liang, Sarah-Jane Smillie et al. · The Journal of Immunology · 2012 · 129 citations

Immune Regulation, Immunology, Cell Death +17