Sylvain Broussy

Recent advances of anti-angiogenic inhibitors targeting VEGF/VEGFR axis

Lei Wang, Wang‐Qing Liu, Sylvain Broussy et al. · Frontiers in Pharmacology · 2024 · 122 citations · Full text

Medicine, Oncology, Pharmacology +16

Use of a Robust Dehydrogenase from an Archael Hyperthermophile in Asymmetric Catalysis−Dynamic Reductive Kinetic Resolution Entry into (<i>S</i>)-Profens

Jacob A. Friest, Yukari Maezato, Sylvain Broussy et al. · Journal of the American Chemical Society · 2010 · 103 citations · Full text

Life Sciences, Biochemistry, Chemistry +16

Biochemical mechanism and biological effects of the inhibition of silent information regulator 1 (SIRT1) by EX-527 (SEN0014196 or selisistat)

Sylvain Broussy, Hanna Laaroussi, Michel Vidal · Journal of Enzyme Inhibition and Medicinal Chemistry · 2020 · 83 citations · Full text

Life Sciences, Biochemistry, Pharmacology +14

Mn(III) Pyrophosphate as an Efficient Tool for Studying the Mode of Action of Isoniazid on the InhA Protein of <i>Mycobacterium tuberculosis</i>

Michel Nguyen, Annaı̈k Quémard, Sylvain Broussy et al. · Antimicrobial Agents and Chemotherapy · 2002 · 81 citations · Full text

Life Sciences, Biochemistry, Microbiology +16

Enantioselective, Ketoreductase-Based Entry into Pharmaceutical Building Blocks: Ethanol as Tunable Nicotinamide Reductant

Sylvain Broussy, Ross W. Cheloha, David B. Berkowitz · Organic Letters · 2008 · 69 citations

Life Sciences, Biochemistry, Medicinal Chemistry +17