David Critton

VISTA is an acidic pH-selective ligand for PSGL-1

Robert J. Johnston, Linhui Julie Su, Jason Pinckney et al. · Nature · 2019 · 375 citations

Biochemistry, G Protein-coupled Receptor, Natural Sciences +4

Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites

Michael J. Ragusa, Barbara Dancheck, David Critton et al. · Nature Structural & Molecular Biology · 2010 · 204 citations · Full text

Protein Phosphatase 1, Protein Function, Signal Transduction +10

Crystal structure of a BRAF kinase domain monomer explains basis for allosteric regulation

Neroshan Thevakumaran, Hugo Lavoie, David Critton et al. · Nature Structural & Molecular Biology · 2014 · 158 citations

Crystal Structure, Protein Function, Signal Transduction +10

A Focused Library of Protein Tyrosine Phosphatase Inhibitors

Anthony B. Comeau, David Critton, Rebecca Page et al. · Journal of Medicinal Chemistry · 2010 · 42 citations · Full text

Drug Target, Peptide Science, Chemical Biology +19

Discovery of Potent and Orally Bioavailable Small Molecule Antagonists of Toll-like Receptors 7/8/9 (TLR7/8/9)

Christopher P. Mussari, Dharmpal S. Dodd, Ratna Kumar Sreekantha et al. · ACS Medicinal Chemistry Letters · 2020 · 37 citations · Full text