The heptad repeat region is a major selection target in MERS-CoV and related coronaviruses

Diego Forni, Giulia Filippi, Rachele Cagliani, +5

Scientific Reports

DFT Dissection of the Reduction Step in H₂ Catalytic Production by [FeFe]-Hydrogenase-Inspired Models: Can the Bridging Hydride Become More Reactive Than the Terminal Isomer?

Giulia Filippi, Federica Arrigoni, Luca Bertini, +2

Inorganic Chemistry

An Evolutionary Analysis of Antigen Processing and Presentation across Different Timescales Reveals Pervasive Selection

Diego Forni, Rachele Cagliani, Claudia Tresoldi, +13

PLoS Genetics

HistocompatibilityGeneticsImmunologyNatural SelectionAntigen Processing +17

Hypotonic stress-induced calcium signaling in Saccharomyces cerevisiae involves TRP-like transporters on the endoplasmic reticulum membrane

Marco Rigamonti, Silvia Groppi, Fiorella Belotti, +4

Cell Calcium

Hypotonic Stress-induced CalciumSignal TransductionMolecular PhysiologyTrp-like TransportersCell Signaling +9

RIG-I-Like Receptors Evolved Adaptively in Mammals, with Parallel Evolution at LGP2 and RIG-I

Rachele Cagliani, Diego Forni, Claudia Tresoldi, +6

Journal of Molecular Biology

Developmental BiologySignal TransductionG Protein-coupled ReceptorFunctional SelectivityEvolutionary Biology +9

A 175 Million Year History of T Cell Regulatory Molecules Reveals Widespread Selection, with Adaptive Evolution of Disease Alleles

Diego Forni, Rachele Cagliani, Uberto Pozzoli, +10

Immunity

ImmunogeneticsAllelic VariantAutoimmune DiseaseGeneticsT-regulatory Cell +8

The mammalian complement system as an epitome of host–pathogen genetic conflicts

Rachele Cagliani, Diego Forni, Giulia Filippi, +7

Molecular Ecology

GeneticsInnate Immune SystemImmunologyInnate ImmunityImmune System +15

Evolutionary Analysis Identifies an MX2 Haplotype Associated with Natural Resistance to HIV-1 Infection

Manuela Sironi, Mara Biasin, Rachele Cagliani, +18

Molecular Biology and Evolution

Positive Selection Drives Evolution at the Host–Filovirus Interaction Surface

Chiara Pontremoli, Diego Forni, Rachele Cagliani, +5

Molecular Biology and Evolution

BiologyVirus StructureViral EvolutionNpc1-c EvolveNatural Sciences +13

Towards biomimetic models of the reduced [FeFe]-hydrogenase that preserve the key structural features of the enzyme active site; a DFT investigation

Sabrina Sicolo, Maurizio Bruschi, Luca Bertini, +5

International Journal of Hydrogen Energy

Enzyme Active SiteCellular EnzymologyBiochemistryNatural SciencesBiocatalysis +7