Adenosine A_2AReceptor Blockade Prevents Synaptotoxicity and Memory Dysfunction Caused by β-Amyloid Peptides via p38 Mitogen-Activated Protein Kinase Pathway

Paula M. Canas, Lisiane O. Porciúncula, Carla G. Silva, +4

Journal of Neuroscience

Caffeine acts through neuronal adenosine A _2A receptors to prevent mood and memory dysfunction triggered by chronic stress

Manuella P. Kaster, Nuno J. Machado, Henrique B. Silva, +12

Proceedings of the National Academy of Sciences

Small intestinal enteropathy with epithelial IgG and complement deposition in children with regressive autism

Franco Torrente, Paul Ashwood, Richard M. Day, +8

Molecular Psychiatry

Complement DepositionRegressive AutismPathogenesisGastroenterologyPediatrics +8

Adenosine Receptor Antagonists Including Caffeine Alter Fetal Brain Development in Mice

Carla G. Silva, Christine Métin, Walid Fazeli, +16

Science Translational Medicine

Adenosine ReceptorsBrain DevelopmentSynaptic TransmissionNeurotransmitterNeurotransmission +18

Astrocytic Adenosine A2A Receptors Control the Amyloid-β Peptide-Induced Decrease of Glutamate Uptake

Marco Matos, Elisabete Augusto, Nuno J. Machado, +3

Journal of Alzheimer s Disease

Behavioral Phenotyping of Parkin-Deficient Mice: Looking for Early Preclinical Features of Parkinson's Disease

Daniel Rial, Adalberto A. Castro, Nuno J. Machado, +9

PLoS ONE

Caffeine regulates frontocorticostriatal dopamine transporter density and improves attention and cognitive deficits in an animal model of attention deficit hyperactivity disorder

Pablo Pandolfo, Nuno J. Machado, Attila Köfalvi, +2

European Neuropsychopharmacology

Cognitive ScienceBrain FunctionNeurophysiologyAnimal ModelNeuropharmacology +6

Type 2 Diabetic and Alzheimer's Disease Mice Present Similar Behavioral, Cognitive, and Vascular Anomalies

Cristina Carvalho, Nuno J. Machado, Paula Mota, +6

Journal of Alzheimer s Disease

Brain DevelopmentNeurochemical BiomarkersAd MiceSocial SciencesAlzheimer's Disease +22

Adenosine A2A Receptors in the Amygdala Control Synaptic Plasticity and Contextual Fear Memory

Ana Patrícia Simões, Nuno J. Machado, Nélio Gonçalves, +7

Neuropsychopharmacology

Contextual Fear MemorySynaptic PlasticityCognitive ScienceNeurobiological MechanismMedicine +11

Blockade of adenosine A2A receptors recovers early deficits of memory and plasticity in the triple transgenic mouse model of Alzheimer's disease

António C. Silva, Cristina Lemos, Francisco Q. Gonçalves, +7

Neurobiology of Disease

Synaptic PlasticityAlzheimer's DiseaseDementiaNeuropharmacologyDegenerative Pathology +7