The proteolytic activity of the paracaspase MALT1 is key in T cell activation

Fabien Rebeaud, Stephan Hailfinger, Anita Posevitz‐Fejfár, +9

Nature Immunology

T-regulatory CellImmunologyPathologyCell DeathImmunologic Mechanism +15

Ferroptotic pores induce Ca2+ fluxes and ESCRT-III activation to modulate cell death kinetics

Lohans Pedrera, Rafael A. Espiritu, Uris Ros, +6

Cell Death and Differentiation

Malt1-dependent RelB cleavage promotes canonical NF-κB activation in lymphocytes and lymphoma cell lines

Stephan Hailfinger, Hendrik Nogai, Christiane Pelzer, +10

Proceedings of the National Academy of Sciences

Differential gene expression in periportal and perivenous mouse hepatocytes

Albert Braeuning, Carina Ittrich, Christoph Köhle, +4

FEBS Journal

Essential role of MALT1 protease activity in activated B cell-like diffuse large B-cell lymphoma

Stephan Hailfinger, Georg Lenz, Vu N. Ngo, +8

Proceedings of the National Academy of Sciences

Lymphoid NeoplasiaMalt1 Protease ActivityEssential RoleOncogenic AgentTumor Growth +13

Dimethyl fumarate induces ferroptosis and impairs NF-κB/STAT3 signaling in DLBCL

Anja Schmitt, Wendan Xu, Philip Bucher, +18

Blood

Zonal gene expression in murine liver: Lessons from tumors

Stephan Hailfinger, Maike Jaworski, Albert Braeuning, +2

Hepatology

PathologyTumor BiologySignaling PathwayHepatobiliary TumorZonal Heterogeneity +15

IκBζ is a key driver in the development of psoriasis

Claus Johansen, Maike Mose, Pernille Ommen, +6

Proceedings of the National Academy of Sciences

IκBζ is a key transcriptional regulator of IL-36–driven psoriasis-related gene expression in keratinocytes

Anne Müller, André Hennig, Sebastian Lorscheid, +4

Proceedings of the National Academy of Sciences

MCL1 is deregulated in subgroups of diffuse large B-cell lymphoma

S-S Wenzel, Michael Grau, Cory Mavis, +11

Leukemia

Tumor BiologyLymphoid NeoplasiaMedicinePathologyCancer Genetics +4