Concepedia

Helen Manne

HM

7

Publications

221

Citations

7

H-Index

2009

Active since

Affiliations

Institute of Cancer Research(Current)

Cancer Research UK

Helen Manne is an author at Institute of Cancer Research specializing in drug discovery, medicinal chemistry, and chemical biology.

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Publications per year

2009–2010

7

Publications

7

Novel Potent BRAF Inhibitors: Toward 1 nM Compounds through Optimization of the Central Phenyl Ring

Delphine Ménard, Ion Niculescu‐Duvaz, H.P. Dijkstra et al. · Journal of Medicinal Chemistry · 2009 · 46 citations · Full text

Novel Hinge Binder Improves Activity and Pharmacokinetic Properties of BRAF Inhibitors

Alfonso Zambon, Delphine Ménard, Bart M. J. M. Suijkerbuijk et al. · Journal of Medicinal Chemistry · 2010 · 37 citations · Full text

Pyridoimidazolones as Novel Potent Inhibitors of v-Raf Murine Sarcoma Viral Oncogene Homologue B1 (BRAF)

Dan Niculescu‐Duvaz, Catherine Gaulon, H.P. Dijkstra et al. · Journal of Medicinal Chemistry · 2009 · 37 citations · Full text

Novel tricyclic pyrazole BRAF inhibitors with imidazole or furan central scaffolds

Dan Niculescu‐Duvaz, Ion Niculescu‐Duvaz, Bart M. J. M. Suijkerbuijk et al. · Bioorganic & Medicinal Chemistry · 2010 · 30 citations · Full text

Development of Novel, Highly Potent Inhibitors of V-RAF Murine Sarcoma Viral Oncogene Homologue B1 (BRAF): Increasing Cellular Potency through Optimization of a Distal Heteroaromatic Group

Bart M. J. M. Suijkerbuijk, Ion Niculescu‐Duvaz, Catherine Gaulon et al. · Journal of Medicinal Chemistry · 2010 · 28 citations · Full text

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