Alexander B. Sigalov

Author

Also Known As

A B Sigalov, A SIGALOV, A. B. Sigalov, A.B. SIGALOV, A.B. Sigalov, Alexander B Sigalov, Alexander B. Sigalov, Alexander Sigalov

Publications

1.6K

Citations

H-Index

Concepts

All Affiliations

SignaBlok (United States)University of Massachusetts Chan Medical School Massachusetts Institute of Technology Indiana University School of Medicine Indiana University – Purdue University Indianapolis

About

Alexander B. Sigalov is an author at SignaBlok (United States) specializing in medicine, immunology, and cell biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	14	18	633
2	Natural Sciences	6	6	242
3	Allergy	3	3	62
4	Engineering	2	2	40
5	Applied Physics	1	1	16

Alexander B. Sigalov

Publications

1.2K

Citations

H-Index

Page 1

	Year	Citations
Homooligomerization of the Cytoplasmic Domain of the T Cell Receptor ζ Chain and of Other Proteins Containing the Immunoreceptor Tyrosine-Based Activation Motif Alexander B. Sigalov, Dikran Aivazian, Lawrence J. Stern Biochemistry	2004	143
Binding of intrinsically disordered proteins is not necessarily accompanied by a structural transition to a folded form Alexander B. Sigalov, Anastasia Zhuravleva, Vladislav Orekhov Biochimie Protein AssemblyDisordered ProteinsProtein FoldingNatural SciencesMolecular Biology	2006	127
Lipid-Binding Activity of Intrinsically Unstructured Cytoplasmic Domains of Multichain Immune Recognition Receptor Signaling Subunits Alexander B. Sigalov, Dikran Aivazian, Vladimir N. Uversky, Biochemistry	2006	111
A novel ligand-independent peptide inhibitor of TREM-1 suppresses tumor growth in human lung cancer xenografts and prolongs survival of mice with lipopolysaccharide-induced septic shock Alexander B. Sigalov International Immunopharmacology Lipopolysaccharide-induced Septic ShockTumor BiologyProlongs SurvivalMedicineImmunology	2014	74
Enzymatic repair of oxidative damage to human apolipoprotein A‐I Alexander B. Sigalov, Lawrence J. Stern FEBS Letters Lipid AssociationLipid Association CharacteristicOxysterolBiochemistryAtherosclerosis	1998	51
The Intrinsically Disordered Cytoplasmic Domain of the T Cell Receptor ζ Chain Binds to the Nef Protein of Simian Immunodeficiency Virus without a Disorder-to-Order Transition Alexander B. Sigalov, Walter M. Kim, Maria Saline, Biochemistry	2008	48
Novel TREM-1 Inhibitors Attenuate Tumor Growth and Prolong Survival in Experimental Pancreatic Cancer Zu T. Shen, Alexander B. Sigalov Molecular Pharmaceutics Prolong SurvivalExperimental Pancreatic CancerImmunologyLethal CancerPathology	2017	48
Structure Induction of the T‐Cell Receptor ζ‐Chain upon Lipid Binding Investigated by NMR Spectroscopy Elke Duchardt, Alexander B. Sigalov, Dikran Aivazian, ChemBioChem Proteinlipid InteractionStructure InductionDetergent MicelleNmr SpectroscopyBiochemistry	2007	41
Immune cell signaling: a novel mechanistic model reveals new therapeutic targets Alexander B. Sigalov Trends in Pharmacological Sciences InflammationSystems BiologySignal TransductionImmunologyImmunologic Mechanism	2006	41
Oxidation of methionine residues affects the structure and stability of apolipoprotein A-I in reconstituted high density lipoprotein particles Alexander B. Sigalov, Lawrence J. Stern Chemistry and Physics of Lipids Methionine ResiduesOxysterolBiochemistryNatural SciencesMolecular Biology	2001	38

Page 1