SARS-CoV-2 mRNA vaccines induce broad CD4+ T cell responses that recognize SARS-CoV-2 variants and HCoV-NL63

Bezawit A. Woldemeskel, Caroline C. Garliss, Joel N. Blankson

Journal of Clinical Investigation

VaccinationSars-cov-2 VariantsSpike ProteinVaccine DevelopmentT Cell Responses +11

The BNT162b2 mRNA Vaccine Elicits Robust Humoral and Cellular Immune Responses in People Living With Human Immunodeficiency Virus (HIV)

Bezawit A. Woldemeskel, Andrew H. Karaba, Caroline C. Garliss, +5

Clinical Infectious Diseases

Humoral ResponseImmunologyHuman Immunodeficiency VirusHealthy DonorsCovid-19 +17

Functional characterization of CD4+ T cell receptors crossreactive for SARS-CoV-2 and endemic coronaviruses

Arbor G. Dykema, Boyang Zhang, Bezawit A. Woldemeskel, +25

Journal of Clinical Investigation

Healthy donor T cell responses to common cold coronaviruses and SARS-CoV-2

Bezawit A. Woldemeskel, Abena K. Kwaa, Caroline C. Garliss, +3

Journal of Clinical Investigation

Targeted PeptidesT Cell ResponsesCommon Cold CoronavirusesCovid-19 PandemicViral Pathogenesis +11

CD4+ T cells from COVID-19 mRNA vaccine recipients recognize a conserved epitope present in diverse coronaviruses

Bezawit A. Woldemeskel, Arbor G. Dykema, Caroline C. Garliss, +3

Journal of Clinical Investigation

ImmunologyCd4 T Cell ResponsesViral Structural ProteinT CellsImmunotherapy +15

mRNA Vaccine-Elicited Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)–Specific T Cells Persist at 6 Months and Recognize the Delta Variant

Bezawit A. Woldemeskel, Caroline C. Garliss, Joel N. Blankson

Clinical Infectious Diseases

SARS-CoV-2 vaccination diversifies the CD4+ spike-reactive T cell repertoire in patients with prior SARS-CoV-2 infection

Arbor G. Dykema, Boyang Zhang, Bezawit A. Woldemeskel, +12

EBioMedicine

SARS-CoV-2–specific immune responses in boosted vaccine recipients with breakthrough infections during the Omicron variant surge

Bezawit A. Woldemeskel, Caroline C. Garliss, Tihitina Y. Aytenfisu, +12

JCI Insight

Boosted Vaccine RecipientsImmunologyImmunodominanceOmicron VariantCovid-19 +15

Proviral location affects cognate peptide–induced virus production and immune recognition of HIV-1–infected T cell clones

Filippo Dragoni, Abena K. Kwaa, Caroline C. Traut, +11

Journal of Clinical Investigation

Viral ReplicationAdaptive Immune SystemImmunologyAntigen ProcessingCd4 T Cell Responses +19

Decay of coronavirus disease 2019 mRNA vaccine-induced immunity in people with HIV

Bezawit A. Woldemeskel, Andrew H. Karaba, Caroline C. Garliss, +6

AIDS

Mrna VaccinesImmunologyHumoral ResponseCd4 T Cell ResponsesHealthy Donors +14