CAR-Engineered NK Cells Targeting Wild-Type EGFR and EGFRvIII Enhance Killing of Glioblastoma and Patient-Derived Glioblastoma Stem Cells

Jianfeng Han, Jianhong Chu, Wing Keung Chan, +15

Scientific Reports

A combinational therapy of EGFR-CAR NK cells and oncolytic herpes simplex virus 1 for breast cancer brain metastases

Xilin Chen, Jianfeng Han, Jianhong Chu, +13

Oncotarget

Transcription Factor Foxo1 Is a Negative Regulator of Natural Killer Cell Maturation and Function

Youcai Deng, Yann M. Kerdiles, Jianhong Chu, +17

Immunity

Transcriptional RegulationNatural Killer CellsNegative RegulatorCell RegulationImmunology +10

Crosstalks between mTORC1 and mTORC2 variagate cytokine signaling to control NK maturation and effector function

Fangjie Wang, Meng Meng, Banghui Mo, +17

Nature Communications

Genetic Modification of T Cells Redirected toward CS1 Enhances Eradication of Myeloma Cells

Jianhong Chu, Shun He, Youcai Deng, +11

Clinical Cancer Research

Yeast-derived nanoparticles remodel the immunosuppressive microenvironment in tumor and tumor-draining lymph nodes to suppress tumor growth

Jialu Xu, Qingle Ma, Yue Zhang, +8

Nature Communications

TGFβ Treatment Enhances Glioblastoma Virotherapy by Inhibiting the Innate Immune Response

Jianfeng Han, Xilin Chen, Jianhong Chu, +11

Cancer Research

MicroRNAs activate natural killer cells through Toll-like receptor signaling

Shun He, Jianhong Chu, Lai‐Chu Wu, +16

Blood

SMAD4 promotes TGF-β–independent NK cell homeostasis and maturation and antitumor immunity

Youwei Wang, Jianhong Chu, Ping Yi, +14

Journal of Clinical Investigation

Engineering micro oxygen factories to slow tumour progression via hyperoxic microenvironments

Weili Wang, Huizhen Zheng, Jun Jiang, +11

Nature Communications