Alexander Hamil

Enhancing Endosomal Escape for Intracellular Delivery of Macromolecular Biologic Therapeutics

Peter Lönn, Apollo D. Kacsinta, Xian-Shu Cui et al. · Scientific Reports · 2016 · 314 citations · Full text

Efficient delivery of RNAi prodrugs containing reversible charge-neutralizing phosphotriester backbone modifications

Bryan R. Meade, Khirud Gogoi, Alexander Hamil et al. · Nature Biotechnology · 2014 · 187 citations · Full text

Cell-based Drug Delivery, Engineering, Biochemistry +7

Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade

Xuefeng Wu, Weizhou Zhang, Joan Font-Burgada et al. · Proceedings of the National Academy of Sciences · 2014 · 108 citations · Full text

Breast Cancer Metastasis, Tumor Biology, Breast Oncology +14

RNAi prodrugs targeting Plk1 induce specific gene silencing in primary cells from pediatric T-acute lymphoblastic leukemia patients

Iryna Kolosenko, Elin Edsbäcker, Ann‐Charlotte Björklund et al. · Journal of Controlled Release · 2017 · 19 citations

Hematological Malignancy, Novel Therapy, Medicine +7

Anti-CD7 allogeneic WU-CART-007 in patients with relapsed/refractory T-cell acute lymphoblastic leukemia/lymphoma: a phase 1/2 trial

Armin Ghobadi, Ibrahim Aldoss, Shannon L. Maude et al. · 2024 · 15 citations · Full text