John C. Widen

Covalent Modifiers: A Chemical Perspective on the Reactivity of α,β-Unsaturated Carbonyls with Thiols via Hetero-Michael Addition Reactions

Paul Jackson, John C. Widen, Daniel A. Harki et al. · Journal of Medicinal Chemistry · 2016 · 548 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +13

AND-gate contrast agents for enhanced fluorescence-guided surgery

John C. Widen, Martina Tholen, Joshua J. Yim et al. · Nature Biomedical Engineering · 2020 · 140 citations · Full text

Engineering, Biomedical Engineering, Surgery +14

Challenges for Targeting SARS-CoV-2 Proteases as a Therapeutic Strategy for COVID-19

Kas Steuten, Heeyoung Kim, John C. Widen et al. · ACS Infectious Diseases · 2021 · 102 citations · Full text

Life Sciences, Infectious Diseases, Medicinal Chemistry +16

The human disease gene LYSET is essential for lysosomal enzyme transport and viral infection

Christopher M. Richards, Sabrina Jabs, Wenjie Qiao et al. · Science · 2022 · 76 citations · Full text

Life Sciences, Biology, Molecular Biology +17

Molecular Basis for the N-Terminal Bromodomain-and-Extra-Terminal-Family Selectivity of a Dual Kinase–Bromodomain Inhibitor

Anand Divakaran, Siva Talluri, Alex Ayoub et al. · Journal of Medicinal Chemistry · 2018 · 72 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +16