Keyan Han

Design, synthesis and biological evaluation of matrine contains benzimidazole derivatives as dual TOPOI and PARP inhibitors for cancer therapy

Gan Qiu, Junwei Xie, Fan Li et al. · European Journal of Medicinal Chemistry · 2024 · 31 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Induction of Apoptosis by Matrine Derivative ZS17 in Human Hepatocellular Carcinoma BEL-7402 and HepG2 Cells through ROS-JNK-P53 Signalling Pathway Activation

Xiang Wang, Sen Zhang, Keyan Han et al. · International Journal of Molecular Sciences · 2022 · 18 citations · Full text

Medicine, Oncology, Pharmacology +15

Novel matrinic acid derivatives bearing 2‐anilinothiazole structure for non‐small cell lung cancer treatment with improved Hsp90 targeting effect

Yiming Xu, Panke Zeng, Haodong Wang et al. · Drug Development Research · 2022 · 13 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13