Dean R. Appling

Increased extracellular matrix synthesis and mRNA in mesangial cells grown in high-glucose medium

Suzanne H. Ayo, Robert A. Radnik, William F. Glass et al. · American Journal of Physiology-Renal Physiology · 1991 · 244 citations

Medicine, Cell Biology, Pathobiology +17

Deletion of <i>Mthfd1l</i> causes embryonic lethality and neural tube and craniofacial defects in mice

Jessica Momb, Jordan P. Lewandowski, Joshua D. Bryant et al. · Proceedings of the National Academy of Sciences · 2012 · 157 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Mitochondrial C1-Tetrahydrofolate Synthase (MTHFD1L) Supports the Flow of Mitochondrial One-carbon Units into the Methyl Cycle in Embryos

Schuyler Pike, Rashmi Rajendra, Karen Artzt et al. · Journal of Biological Chemistry · 2009 · 117 citations · Full text

Life Sciences, Biochemistry, Developmental Biology +13

Role of Mitochondrial and Cytoplasmic Serine Hydroxymethyltransferase Isozymes in <i>de Novo</i> Purine Synthesis in <i>Saccharomyces cerevisiae</i>

Evdokia Kastanos, Yakov Y. Woldman, Dean R. Appling · Biochemistry · 1997 · 115 citations

Life Sciences, Biochemistry, Genetics +16

In vitro evidence for the involvement of mitochondrial folate metabolism in the supply of cytoplasmic one-carbon units.

Charles Barlowe, Dean R. Appling · PubMed · 1988 · 112 citations

Life Sciences, Biochemistry, Molecular Biology +15