T. Blake Monroe

A carnosine analog mitigates metabolic disorders of obesity by reducing carbonyl stress

Ethan J. Anderson, Giulio Vistoli, Lalage A. Katunga et al. · Journal of Clinical Investigation · 2018 · 111 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +14

Lipid peroxidation products induce carbonyl stress, mitochondrial dysfunction, and cellular senescence in human and murine cells

T. Blake Monroe, Ann V. Hertzel, Deborah M. Dickey et al. · Aging Cell · 2024 · 32 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Biochemical characterization of the catecholaldehyde reactivity of l-carnosine and its therapeutic potential in human myocardium

Margaret-Ann M. Nelson, Zachariah J. Builta, T. Blake Monroe et al. · Amino Acids · 2018 · 27 citations · Full text

Medicine, Biochemistry, Cardiology +9

Enhanced Catecholamine Flux and Impaired Carbonyl Metabolism Disrupt Cardiac Mitochondrial Oxidative Phosphorylation in Diabetes Patients

Margaret-Ann M. Nelson, Jimmy T. Efird, Kimberly Kew et al. · Antioxidants and Redox Signaling · 2020 · 18 citations · Full text

Life Sciences, Biochemistry, Cardiology +17

A Catecholaldehyde Metabolite of Norepinephrine Induces Myofibroblast Activation and Toxicity via the Receptor for Advanced Glycation Endproducts: Mitigating Role of <scp>l</scp>-Carnosine

T. Blake Monroe, Ethan J. Anderson · Chemical Research in Toxicology · 2021 · 12 citations · Full text

Life Sciences, Biochemistry, Physiology +14