Mengnan Tian

The GABRG2 nonsense mutation, Q40X, associated with Dravet syndrome activated NMD and generated a truncated subunit that was partially rescued by aminoglycoside-induced stop codon read-through

Xuan Huang, Mengnan Tian, Ciria C. Hernández et al. · Neurobiology of Disease · 2012 · 46 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

The Intronic<i>GABRG2</i>Mutation, IVS6+2T→G, Associated with Childhood Absence Epilepsy Altered Subunit mRNA Intron Splicing, Activated Nonsense-Mediated Decay, and Produced a Stable Truncated γ2 Subunit

Mengnan Tian, Robert L. Macdonald · Journal of Neuroscience · 2012 · 40 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Impaired surface αβγ GABAA receptor expression in familial epilepsy due to a GABRG2 frameshift mutation

Mengnan Tian, Davide Mei, Elena Freri et al. · Neurobiology of Disease · 2012 · 31 citations · Full text

Life Sciences, Genetics, Neuroscience +14

Overexpressing wild‐type γ2 subunits rescued the seizure phenotype in <i>Gabrg2</i>^{<i>+/Q390X</i>} Dravet syndrome mice

Xuan Huang, Chengwen Zhou, Mengnan Tian et al. · Epilepsia · 2017 · 24 citations · Full text

Life Sciences, Genetics, Neuroscience +17