Ioannis Grapsas

Loss of individual electrostatic interactions between aminoglycoside antibiotics and resistance enzymes as an effective means to overcoming bacterial drug resistance

Juliatiek Roestamadji, Ioannis Grapsas, Shahriar Mobashery · Journal of the American Chemical Society · 1995 · 64 citations

Altmetric Attention Score, Antibiotic Resistance, Drug Resistance +18

Mechanism-Based Inactivation of Bacterial Aminoglycoside 3'-Phosphotransferases

Juliatiek Roestamadji, Ioannis Grapsas, Shahriar Mobashery · Journal of the American Chemical Society · 1995 · 53 citations

Bacteriology, Altmetric Attention Score, Bacterial Pathogens +18

Properties of a Bifunctional Bacterial Antibiotic Resistance Enzyme That Catalyzes ATP-Dependent 2‘‘-Phosphorylation and Acetyl-CoA-Dependent 6‘-Acetylation of Aminoglycosides

Eduardo Azucena, Ioannis Grapsas, Shahriar Mobashery · Journal of the American Chemical Society · 1997 · 42 citations

Altmetric Attention Score, Chemical Biology, Antibiotic Resistance +17

N-(tert-Butoxycarbonyloxy)-5-norbornene-endo-2,3-dicarboximide, a Reagent for the Regioselective Introduction of the tert-Butoxycarbonyl (BOC) Protective Group at Unhindered Amines: Application to Amino glycoside Chemistry

Ioannis Grapsas, Young June Cho, Shahriar Mobashery · The Journal of Organic Chemistry · 1994 · 30 citations

Unhindered Amines, Bioorganic Chemistry, Engineering +14

Conscripting the Active-Site Zinc Ion in Carboxypeptidase A in Inactivation Chemistry by a New Type of Irreversible Enzyme Inactivator

Yasuhiro Tanaka, Ioannis Grapsas, Srikanth Dakoji et al. · Journal of the American Chemical Society · 1994 · 27 citations

Engineering, Chemical Analysis, Molecular Biology +17