Sam P. de Visser

A Model “Rebound” Mechanism of Hydroxylation by Cytochrome P450:  Stepwise and Effectively Concerted Pathways, and Their Reactivity Patterns

François Ogliaro, Nathan Harris, Shimrit Cohen et al. · Journal of the American Chemical Society · 2000 · 397 citations

Life Sciences, Biochemistry, Chemistry +15

A Proton-Shuttle Mechanism Mediated by the Porphyrin in Benzene Hydroxylation by Cytochrome P450 Enzymes

Sam P. de Visser, Sason Shaik · Journal of the American Chemical Society · 2003 · 368 citations

Life Sciences, Biochemistry, Chemistry +16

External Electric Field Will Control the Selectivity of Enzymatic-Like Bond Activations

Sason Shaik, Sam P. de Visser, Devesh Kumar · Journal of the American Chemical Society · 2004 · 336 citations

Pharmacy, Chemistry, Catalysis +15

Searching for the Second Oxidant in the Catalytic Cycle of Cytochrome P450:  A Theoretical Investigation of the Iron(III)-Hydroperoxo Species and Its Epoxidation Pathways

François Ogliaro, Sam P. de Visser, Shimrit Cohen et al. · Journal of the American Chemical Society · 2002 · 304 citations

Life Sciences, Biochemistry, Chemistry +15

What Factors Affect the Regioselectivity of Oxidation by Cytochrome P450? A DFT Study of Allylic Hydroxylation and Double Bond Epoxidation in a Model Reaction

Sam P. de Visser, François Ogliaro, Pankaz K. Sharma et al. · Journal of the American Chemical Society · 2002 · 302 citations

Natural Sciences, Biochemistry, Chemistry +15