James A. Sikorski

A Nonpeptidyl Mimic of Superoxide Dismutase with Therapeutic Activity in Rats

Daniela Salvemini, Zhiqiang Wang, Jay L. Zweíer et al. · Science · 1999 · 499 citations

Inflammation, Anti-inflammatory, Biochemistry +15

Recent advances in therapeutic chalcones

Liming Ni, Charles Q. Meng, James A. Sikorski · Expert Opinion on Therapeutic Patents · 2004 · 201 citations

Lead Compounds, Synthetic Chalcone Compounds, Medicinal Chemistry +14

Structure and topological symmetry of the glyphosate target 5-enolpyruvylshikimate-3-phosphate synthase: a distinctive protein fold.

William C. Stallings, S. Abdel‐Meguid, Louis W. Lim et al. · Proceedings of the National Academy of Sciences · 1991 · 132 citations · Full text

Protein Assembly, Biomolecular Structure Prediction, Two-domain Structure +16

EPSP Synthase: The Design and Synthesis of Bisubstrate Inhibitors Incorporating Novel 3-Phosphate Mimics

James A. Sikorski, Michael J. Miller, Diane S. Braccolino et al. · Phosphorus, sulfur, and silicon and the related elements · 1993 · 130 citations

Combinatorial Chemistry, Diversity Oriented Synthesis, Biosynthesis +14

A tetrahedral intermediate in the EPSP synthase reaction observed by rapid quench kinetics

Karen S. Anderson, James A. Sikorski, Kenneth A. Johnson · Biochemistry · 1988 · 128 citations