Ruben Wälchli

Design and operation of a continuous integrated monoclonal antibody production process

Fabian Steinebach, Nicole Ulmer, Moritz Wolf et al. · Biotechnology Progress · 2017 · 128 citations

Process‐wide control and automation of an integrated continuous manufacturing platform for antibodies

Fabian Feidl, Sebastian Vogg, Moritz Wolf et al. · Biotechnology and Bioengineering · 2020 · 94 citations

Engineering, Industrial Engineering, Smart Manufacturing +22

Understanding mAb aggregation during low pH viral inactivation and subsequent neutralization

Ruben Wälchli, Mariana Ressurreição, Sebastian Vogg et al. · Biotechnology and Bioengineering · 2019 · 54 citations

Viral Replication, Engineering, Immunology +21

Accelerated Aggregation Studies of Monoclonal Antibodies: Considerations for Storage Stability

Ruben Wälchli, Pieter‐Jan Vermeire, Jan Massant et al. · Journal of Pharmaceutical Sciences · 2019 · 48 citations · Full text

Relationship of PEG-induced precipitation with protein-protein interactions and aggregation rates of high concentration mAb formulations at 5 °C

Ruben Wälchli, Francesca Fanizzi, Jan Massant et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2020 · 23 citations · Full text