Jérôme Durivault

Genetic Disruption of the Multifunctional CD98/LAT1 Complex Demonstrates the Key Role of Essential Amino Acid Transport in the Control of mTORC1 and Tumor Growth

Yann Cormerais, Sandy Giuliano, Renaud LeFloch et al. · Cancer Research · 2016 · 240 citations

Multifunctional Cd98/lat1 Complex, Mtorc1 Activity, Molecular Biology +23

Double genetic disruption of lactate dehydrogenases A and B is required to ablate the “Warburg effect” restricting tumor growth to oxidative metabolism

Maša Ždralević, Almut Brand, Lorenza Di Ianni et al. · Journal of Biological Chemistry · 2018 · 239 citations · Full text

Tumor Biology, Biochemistry, Medicine +11

Genetic Ablation of the Cystine Transporter xCT in PDAC Cells Inhibits mTORC1, Growth, Survival, and Tumor Formation via Nutrient and Oxidative Stresses

Boutaina Daher, Scott K. Parks, Jérôme Durivault et al. · Cancer Research · 2019 · 195 citations

The HIF-1–Inducible Lysyl Oxidase Activates HIF-1 via the Akt Pathway in a Positive Regulation Loop and Synergizes with HIF-1 in Promoting Tumor Cell Growth

Floriane Pez, Frédéric Dayan, Jérôme Durivault et al. · Cancer Research · 2011 · 183 citations · Full text

The glutamine transporter ASCT2 (SLC1A5) promotes tumor growth independently of the amino acid transporter LAT1 (SLC7A5)

Yann Cormerais, Pierre André Massard, Milica Vučetić et al. · Journal of Biological Chemistry · 2018 · 167 citations · Full text

Tumor Biology, Signal Transduction, Oncogenic Agent +10