Kotaro Akaki

Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis

Nobuyuki Kakiuchi, Kenichi Yoshida, Motoi Uchino et al. · Nature · 2019 · 245 citations

Inflammation, Frequent Mutations, Autoimmune Disease +9

N4BP1 restricts HIV-1 and its inactivation by MALT1 promotes viral reactivation

Daichi Yamasoba, Kei Sato, Takuya Ichinose et al. · Nature Microbiology · 2019 · 77 citations

Viral Reactivation, Human Retrovirus, Pathogenesis +9

Regnase-1 Prevents Pulmonary Arterial Hypertension Through mRNA Degradation of Interleukin-6 and Platelet-Derived Growth Factor in Alveolar Macrophages

Ai Yaku, Tadakatsu Inagaki, Ryotaro Asano et al. · Circulation · 2022 · 62 citations · Full text

Translation-dependent unwinding of stem–loops by UPF1 licenses Regnase-1 to degrade inflammatory mRNAs

Takashi Mino, Noriki Iwai, Masayuki Endo et al. · Nucleic Acids Research · 2019 · 52 citations · Full text

Engineering, Immunology, Inflammatory Mrnas +18

IRAK1-dependent Regnase-1-14-3-3 complex formation controls Regnase-1-mediated mRNA decay

Kotaro Akaki, Kosuke Ogata, Yuhei Yamauchi et al. · eLife · 2021 · 16 citations · Full text

Immune Regulation, Immunology, Innate Immunity +19